Arthritis

• Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (PubMed)
• The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis(PubMed)
• Involvement of the endocannabinoid system in osteoarthritis pain (PubMed)
• The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55 (PubMed)
• Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint(PLOS)
• Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis ( BMC Musculoskeletal Disorders)
• Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1b induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes (Osteoarthritis Research Society International)
• Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis (Centre for Analytical Bioscience)